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【文献】癌症与3D基因组

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licheng 发表于 2016-1-14 11:20:27 | 显示全部楼层 |阅读模式
综述

http://www.ncbi.nlm.nih.gov/pubmed/26855137
Curr Opin Genet Dev. 2016 Feb 5;36:1-7. doi: 10.1016/j.gde.2016.01.002. [Epub ahead of print]
The three-dimensional cancer genome.

http://www.ncbi.nlm.nih.gov/pubmed/26553406
Nucleus. 2015;6(5):382-93. doi: 10.1080/19491034.2015.1106676.
3D genome organization in health and disease: emerging opportunities in cancer translational medicine.

3D癌症基因组

http://www.ncbi.nlm.nih.gov/pubmed/27053337
Genome Res. 2016 Apr 6. pii: gr.201517.115. [Epub ahead of print]
Three-dimensional disorganisation of the cancer genome occurs coincident with long range genetic and epigenetic alterations.

http://www.ncbi.nlm.nih.gov/pubmed/26921073
Chromosoma. 2016 Feb 27. [Epub ahead of print]
Chromosomal aneuploidies induced upon Lamin B2 depletion are mislocalized in the interphase nucleus.

http://www.ncbi.nlm.nih.gov/pubmed/26415882
Genome Biol. 2015 Sep 28;16:214. doi: 10.1186/s13059-015-0768-0.
Chromatin interaction analysis reveals changes in small chromosome and telomere clustering between epithelial and breast cancer cells.

http://www.ncbi.nlm.nih.gov/pubmed/25470140
PLoS One. 2014 Dec 3;9(12):e113354. doi: 10.1371/journal.pone.0113354. eCollection 2014.
Estrogen induces global reorganization of chromatin structure in human breast cancer cells.

http://www.ncbi.nlm.nih.gov/pubmed/22615383
Proc Natl Acad Sci U S A. 2012 Jun 5;109(23):9083-8. doi: 10.1073/pnas.1112570109. Epub 2012 May 21.
Oncogene-mediated alterations in chromatin conformation.

3D基因组与癌症GWAS和变异位点

http://www.ncbi.nlm.nih.gov/pubmed/25695508
Nat Commun. 2015 Feb 19;6:6178. doi: 10.1038/ncomms7178.
Capture Hi-C identifies the chromatin interactome of colorectal cancer risk loci.

http://www.ncbi.nlm.nih.gov/pubmed/25122612
Genome Res. 2014 Nov;24(11):1854-68. doi: 10.1101/gr.175034.114. Epub 2014 Aug 13.
Unbiased analysis of potential targets of breast cancer susceptibility loci by Capture Hi-C.

染色体易位和空间位置的关系

http://www.ncbi.nlm.nih.gov/pubmed/22341456
Spatial organization of the mouse genome and its role in recurrent chromosomal translocations.
Cell. 2012 Mar 2;148(5):908-21.

http://www.ncbi.nlm.nih.gov/pubmed/23236267
Genomic hallmarks of genes involved in chromosomal translocations in hematological cancer.
PLoS Comput Biol. 2012;8(12):e1002797.
血液肿瘤中,融合基因一般在早期复制区域,但融合的基因的相互位置不能解释临床发生频率。

http://www.ncbi.nlm.nih.gov/pubmed/21962511
Genome-wide translocation sequencing reveals mechanisms of chromosome breaks and rearrangements in B cells.
Cell. 2011 Sep 30;147(1):107-19.

http://www.ncbi.nlm.nih.gov/pubmed/21962510
Translocation-capture sequencing reveals the extent and nature of chromosomal rearrangements in B lymphocytes.
Cell. 2011 Sep 30;147(1):95-106.

http://www.ncbi.nlm.nih.gov/pubmed/22101486
High order chromatin architecture shapes the landscape of chromosomal alterations in cancer.
Nat Biotechnol. 2011 Nov 20;29(12):1109-13.
DNA拷贝数变化(CNV)和三维结构的关系

http://www.ncbi.nlm.nih.gov/pubmed/22101487
DNA replication timing and long-range DNA interactions predict mutational landscapes of cancer genomes.
Nat Biotechnol. 2011 Nov 20;29(12):1103-8.
复制时期相同的DNA区域的空间距离较近,CNV也容易发生在这些区域

http://www.ncbi.nlm.nih.gov/pubmed/23028501
PLoS One. 2012;7(9):e44196. doi: 10.1371/journal.pone.0044196. Epub 2012 Sep 28.
Three-dimensional genome architecture influences partner selection for chromosomal translocations in human disease.
癌症中的融合基因在正常细胞中的相互作用频率较高。

http://www.ncbi.nlm.nih.gov/pubmed/22314321
Nature. 2012 Feb 7;484(7392):69-74. doi: 10.1038/nature10909.
DNA damage defines sites of recurrent chromosomal translocations in B lymphocytes.

http://www.ncbi.nlm.nih.gov/pubmed/17622196
PLoS Biol. 2007 Aug;5(8):e192.
Myc dynamically and preferentially relocates to a transcription factory occupied by Igh.

http://www.ncbi.nlm.nih.gov/pubmed/25482199
Nucleus. 2014 Sep-Oct;5(5):474-81. doi: 10.4161/nucl.36233.
Nucleolar tethering mediates pairing between the IgH and Myc loci.

https://www.ncbi.nlm.nih.gov/pubmed/26276627
Cell.[/url] 2015 Aug 13;162(4):708-11. doi: 10.1016/j.cell.2015.07.034.
Somatic Rearrangement in B Cells: It's (Mostly) Nuclear Physics.
综述:染色体重组和空间位置的关系
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