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【文献】癌症药物敏感性与耐药性

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licheng 发表于 2016-3-22 09:08:59 | 显示全部楼层 |阅读模式
http://www.ncbi.nlm.nih.gov/pubmed/26735014
Nature. 2016 Jan 21;529(7586):413-7. doi: 10.1038/nature16508. Epub 2016 Jan 6.
Response and resistance to BET bromodomain inhibitors in triple-negative breast cancer.

http://www.ncbi.nlm.nih.gov/pubmed/26710886
Leukemia. 2015 Dec 29. doi: 10.1038/leu.2015.361. [Epub ahead of print]
Single-cell analysis of targeted transcriptome predicts drug sensitivity of single cells within human myeloma tumors.

http://www.ncbi.nlm.nih.gov/pubmed/26570998
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Pharmacogenomic agreement between two cancer cell line data sets.

http://www.ncbi.nlm.nih.gov/pubmed/26416732
Nature. 2015 Oct 8;526(7572):263-7. doi: 10.1038/nature14969. Epub 2015 Sep 30.
The genomic landscape of response to EGFR blockade in colorectal cancer.

http://www.ncbi.nlm.nih.gov/pubmed/26367798
Nature. 2015 Sep 24;525(7570):543-7. doi: 10.1038/nature14898. Epub 2015 Sep 14.
Transcriptional plasticity promotes primary and acquired resistance to BET inhibition.

http://www.ncbi.nlm.nih.gov/pubmed/26367796
Nature. 2015 Sep 24;525(7570):538-42. doi: 10.1038/nature14888. Epub 2015 Sep 14.
BET inhibitor resistance emerges from leukaemia stem cells.

http://www.ncbi.nlm.nih.gov/pubmed/26383955
Science. 2015 Sep 18;349(6254):1351-6. doi: 10.1126/science.aab0917.
RNA-Seq of single prostate CTCs implicates noncanonical Wnt signaling in antiandrogen resistance.

http://www.ncbi.nlm.nih.gov/pubmed/26308893
Nature. 2015 Sep 10;525(7568):261-4. doi: 10.1038/nature14971. Epub 2015 Aug 26.
A spatial model predicts that dispersal and cell turnover limit intratumour heterogeneity.

http://www.ncbi.nlm.nih.gov/pubmed/26017449
Nature. 2015 May 28;521(7553):489-94. doi: 10.1038/nature14410.
Whole-genome characterization of chemoresistant ovarian cancer.

http://www.ncbi.nlm.nih.gov/pubmed/25765070
Science. 2015 Apr 3;348(6230):124-8. doi: 10.1126/science.aaa1348. Epub 2015 Mar 12.
Cancer immunology. Mutational landscape determines sensitivity to PD-1 blockade in non-small cell lung cancer.

http://www.ncbi.nlm.nih.gov/pubmed/25394791
Science. 2014 Dec 19;346(6216):1480-6. doi: 10.1126/science.1254721. Epub 2014 Nov 13.
Patient-derived models of acquired resistance can identify effective drug combinations for cancer.

http://www.ncbi.nlm.nih.gov/pubmed/25013076
Science. 2014 Jul 11;345(6193):216-20. doi: 10.1126/science.1253533.
Cancer therapy. Ex vivo culture of circulating breast tumor cells for individualized testing of drug susceptibility.

http://www.ncbi.nlm.nih.gov/pubmed/24723613
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Mapping the cellular response to small molecules using chemogenomic fitness signatures.

http://www.ncbi.nlm.nih.gov/pubmed/24284626
Nature. 2013 Dec 19;504(7480):389-93. doi: 10.1038/nature12831. Epub 2013 Nov 27.
Inconsistency in large pharmacogenomic studies.
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