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【文献】非整倍体与癌症/干细胞

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licheng 发表于 2016-3-21 16:02:35 | 显示全部楼层 |阅读模式
非整倍体与干细胞
http://www.ncbi.nlm.nih.gov/pubmed/24899134
Protein Cell. 2014;5(8):569-79. doi: 10.1007/s13238-014-0073-9. Epub 2014 Jun 5.
Aneuploidy in pluripotent stem cells and implications for cancerous transformation.

http://www.ncbi.nlm.nih.gov/pubmed/25198699
Nat Commun. 2014 Sep 8;5:4825. doi: 10.1038/ncomms5825.
Aneuploidy induces profound changes in gene expression, proliferation and tumorigenicity of human pluripotent stem cells.

http://www.ncbi.nlm.nih.gov/pubmed/26573328
Nat Commun. 2015 Nov 17;6:8894. doi: 10.1038/ncomms9894.
Aneuploidy causes premature differentiation of neural and intestinal stem cells.

http://www.ncbi.nlm.nih.gov/pubmed/24937170
Sci Rep. 2014 Jun 17;4:5324. doi: 10.1038/srep05324.
Chromosome instability in mouse embryonic stem cells.


非整倍体与癌症
http://www.ncbi.nlm.nih.gov/pubmed/26876972
Nat Commun. 2016 Feb 15;7:10754. doi: 10.1038/ncomms10754.
The presence of extra chromosomes leads to genomic instability.

http://www.ncbi.nlm.nih.gov/pubmed/23374337
Cell. 2013 Jan 31;152(3):394-405. doi: 10.1016/j.cell.2012.11.043.
Gene copy-number alterations: a cost-benefit analysis.

https://www.ncbi.nlm.nih.gov/pubmed/18974345
Science. 2008 Oct 31;322(5902):703-9. doi: 10.1126/science.1160058.
Aneuploidy affects proliferation and spontaneous immortalization in mammalian cells.

https://www.ncbi.nlm.nih.gov/pubmed/26956415
Sci Rep. 2016 Mar 9;6:22828. doi: 10.1038/srep22828.
Selective advantage of trisomic human cells cultured in non-standard conditions.

https://www.ncbi.nlm.nih.gov/pubmed/22565320
EMBO Rep. 2012 Jun 1;13(6):501-14. doi: 10.1038/embor.2012.55.
Losing balance: the origin and impact of aneuploidy in cancer.

https://www.ncbi.nlm.nih.gov/pubmed/22968442
Mol Syst Biol. 2012;8:608. doi: 10.1038/msb.2012.40.
Global analysis of genome, transcriptome and proteome reveals the response to aneuploidy in human cells.

https://www.ncbi.nlm.nih.gov/pubmed/21872963
Trends Genet. 2011 Nov;27(11):446-53. doi: 10.1016/j.tig.2011.07.003. Epub 2011 Aug 26.
The aneuploidy paradox: costs and benefits of an incorrect karyotype.

https://www.ncbi.nlm.nih.gov/pubmed/17702937
Science. 2007 Aug 17;317(5840):916-24.
Effects of aneuploidy on cellular physiology and cell division in haploid yeast.




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